NCF1/p47 phox(Ser359) Antibody, HRP Conjugated

  • Catalog name: bs-11445R-HRP
  • Supplier name: Bioss Primary Conjugated Antibodies
  • Size: 0.1ml
  • Price: 368.00€
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  • Long name NCF1/p47 phox(Ser359) Antibody, HRP Conjugated
  • Category Conjugated Primary Antibodies
  • Conjugation HRP
  • Host Organism Rabbit (Oryctolagus cuniculus)
  • Target Antigen NCF1/p47 phox Ser359
  • Specificity This is a highly specific antibody against NCF1/p47 phox Ser359.
  • Modification Phosphorylation
  • Modification site Ser359
  • Clonality Polyclonal
  • Clone Polyclonal antibody
  • Concentration 1ug per 1ul
  • Source KLH conjugated synthetic phosphopeptide derived from human NCF1 around the phosphorylation site of Ser359
  • Gene ID number 653361
  • Tested applications WB, IHC-P
  • Recommended dilutions WB(1:100-1000), IHC-P(1:100-500)
  • Crossreactivity Human, Rat
  • Crossreactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47-phox and p67-phox. The cytosolic proteins p47-phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47-phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47-phox, suggesting that p47-phox may faciliate the transport of p67-phox to the membrane.
  • Purification method This antibody was purified via Protein A.
  • Storage conditions Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission N/A
  • Synonyms NCF1Ser359; p47 phoxSer359; NCF1 phospho S359; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NCF 47K; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; NOXO2; p47 phox; p47phox; ;SH3 and PX domain containing protein 1A; SH3PXD1A; NADPH oxidase p47 phox; NCF1_HUMAN.
  • Properties If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
  • Additional conjugation HRP Conjugated
  • French translation anticorps