Other names
phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; protein Noxa; phorbol-12-myristate-13-acetate-induced protein 1; Protein Noxa
Gene name
NOXA
Gene name synonims
N/A
Other gene names
Pmaip1; Pmaip1; Noxa; Noxa
Category
Antibodies
Clonality
Polyclonal
Immunoglobulin isotype
Polyclonal IgG
Clone
Polyclonal antibody
Host organism
Rabbit
Species reactivity
Mouse
Specificity and cross-reactivity
NOXA This item recognises murine Noxa, an 11kDa member of the BH3-only proapoptotic protein family. Noxa is localised to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering the activity of anti-apoptotic Bcl-2-like proteins. It can be upregulated by mitogenic activation, independently of p53. In humans, along with Mcl-1 it is thought to form a selective pathway that restrains lymphocyte proliferation.
Purification method
N/A
Form/Appearance
Purified (Purified IgG - liquid)
Concentration
IgG concentration 500ug/1000ul
Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Tested for:
Immunohistology - Paraffin (IHC), Western Blot (WB)
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.