Other names
phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; protein Noxa; PMA-induced protein 1; immediate-early-response protein APR; adult T cell leukemia-derived PMA-responsive; phorbol-12-myristate-13-acetate-induced protein 1; Immediate-early-response protein APR; Protein Noxa
Gene name
NOXA
Gene name synonims
N/A
Other gene names
PMAIP1; PMAIP1; APR; NOXA; NOXA; PMA-induced protein 1
Category
Antibodies
Clonality
Polyclonal
Immunoglobulin isotype
Polyclonal IgG
Clone
Polyclonal antibody
Host organism
Goat
Species reactivity
Human
Specificity and cross-reactivity
NOXA This item specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, and acts as promoter of caspase and apoptosis activation. _x000D__x000D_Noxa is a transcriptional target of p53, p73 and BH3-only proteins, and competes with, and displaces, the proapoptotic proteins BAK1, and BIM, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), thereby influencing apoptosis versus cell survival.
Purification method
N/A
Form/Appearance
Purified (Purified IgG - liquid)
Concentration
IgG concentration 500ug/1000ul
Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Tested for:
Western Blot (WB), ELISA (EIA)
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.