Anti-GAD65 (Polyclonal), ALEXA Fluor 594

  • Catalog name: GENTObs-0400R-A594
  • Supplier name: Bioss Polyclonal Antibodies
  • Size: 100 microliters
  • Price: 489.00€
  • Type Conjugated Primary Antibody
  • Conjugated with ALEXA FLUOR® 594
  • Host organism Rabbit (Oryctolagus cuniculus)
  • Target Protein/Peptide GAD65
  • Specificity This antibody reacts specifically with GAD65
  • Modification No modification has been applied to this antibody
  • Modification site None
  • Clonality Polyclonal Antibody
  • Clone Polyclonal Antibodies
  • Concentration 1ug per 1ul
  • Subcellular locations Cytoplasm
  • Antigen Source KLH conjugated synthetic peptide derived from human GAD65
  • Gene ID 2572
  • Swiss Prot Q05329
  • Applications IF(IHC-P)
  • Applications with corresponding dilutions IF(IHC-P)(1:50-200)
  • Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
  • Purification method Purified by Protein A.
  • Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission 590nm/617nm
  • Synonyms GAD65; Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; GAD2
  • Also known as GAD65 Polyclonal Antibody
  • Other name Anti-GAD65 Polyclonal
  • Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties For facs or microscopy Alexa 1 conjugate.
  • Conjugation Alexa Fluor,ALEXA FLUOR® 594
  • Conjugated Alexa conjugate 1
  • Group Polyclonals and antibodies
  • About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.