Anti-ADAMTS10 (Polyclonal), ALEXA Fluor 594

  • Catalog name: GENTObs-6588R-A594
  • Supplier name: Bioss Polyclonal Antibodies
  • Size: 100 microliters
  • Price: 489.00€
  • Type Conjugated Primary Antibody
  • Conjugated with ALEXA FLUOR® 594
  • Host organism Rabbit (Oryctolagus cuniculus)
  • Target Protein/Peptide ADAMTS10
  • Specificity This antibody reacts specifically with ADAMTS10
  • Modification No modification has been applied to this antibody
  • Modification site None
  • Clonality Polyclonal Antibody
  • Clone Polyclonal Antibodies
  • Concentration 1ug per 1ul
  • Subcellular locations N/A
  • Antigen Source KLH conjugated synthetic peptide derived from human ADAMTS10
  • Gene ID 81794
  • Swiss Prot N/A
  • Applications IF(IHC-P)
  • Applications with corresponding dilutions IF(IHC-P)(1:50-200)
  • Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.
  • Purification method Purified by Protein A.
  • Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission 590nm/617nm
  • Synonyms A disintegrin and metalloproteinase with thrombospondin mots 10; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot, 10; ADAM metallopeptidase with thrombospondin type 1 mot 10; ADAM TS10; EC 3.4.24; WMS; ATS10_HUMAN.
  • Also known as ADAMTS10 Polyclonal Antibody
  • Other name Anti-ADAMTS10 Polyclonal
  • Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties For facs or microscopy Alexa 1 conjugate.
  • Conjugation Alexa Fluor,ALEXA FLUOR® 594
  • Conjugated Alexa conjugate 1
  • Group Polyclonals and antibodies
  • About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.