Neuropilin-1 Antibody, ALEXA FLUOR 594

  • Catalog name: bs-0693R-A594
  • Supplier name: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
  • Size: 100ul
  • Price: 332.75€
  • Long name Neuropilin-1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as Anti-Neuropilin 1 PAb ALEXA FLUOR 594
  • Category Conjugated Primary Antibodies
  • Conjugated with ALEXA FLUOR® 594
  • Host Organism Rabbit (Oryctolagus cuniculus)
  • Target Antigen Neuropilin 1
  • Specificity This is a highly specific antibody against Neuropilin 1.
  • Modification Unmodified
  • Modification Site None
  • Clonality Polyclonal
  • Clone Polyclonal antibody
  • Concentration 1ug per 1ul
  • Immunogen range 880-923/923
  • Subcellular location Cytoplasm
  • Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human neuropilin-1
  • Gene ID Number 8829
  • Swiss Prot O14786
  • Tested applications IF(IHC-P)
  • Recommended dilutions IF(IHC-P)(1:50-200)
  • Crossreactivity Human, Mouse, Rat
  • Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
  • Purification Purified by Protein A.
  • Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission 590nm/617nm
  • Synonyms NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; NRP1
  • Properties For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation Alexa Fluor,ALEXA FLUOR® 594
  • Conjugated Alexa conjugate 1
  • French translation anticorps