Long name E2F1 (Ser364) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known as Anti-E2F1 Ser364 PAb ALEXA FLUOR 555
Category Conjugated Primary Antibodies
Conjugated with ALEXA FLUOR® 555
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen E2F1 Ser364
Specificity This is a highly specific antibody against E2F1 Ser364.
Modification Site Ser364
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 350-370/437
Subcellular location Nucleus
Source KLH conjugated synthetic phosphopeptide derived from human E2F1 around the phosphorylation site of Ser364
Gene ID Number 1869
Swiss Prot Q01094
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission 553nm/568nm
Synonyms RBP3; E2F-1; RBAP1; RBBP3; Transcription factor E2F1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1; E2F1
Properties For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.