Zonula occludens protein 3 Antibody, ALEXA FLUOR 647

  • Catalog name: bs-13755R-A647
  • Supplier name: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
  • Size: 100ul
  • Price: 332.75€
  • Long name Zonula occludens protein 3 Antibody, ALEXA FLUOR 647 Conjugated
  • Also known as Anti-Zonula occludens protein 3 PAb ALEXA FLUOR 647
  • Category Conjugated Primary Antibodies
  • Conjugated with ALEXA FLUOR® 647
  • Host Organism Rabbit (Oryctolagus cuniculus)
  • Target Antigen Zonula occludens protein 3
  • Specificity This is a highly specific antibody against Zonula occludens protein 3.
  • Modification Unmodified
  • Modification Site None
  • Clonality Polyclonal
  • Clone Polyclonal antibody
  • Concentration 1ug per 1ul
  • Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Zonula occludens protein 3
  • Tested applications IF(IHC-P)
  • Recommended dilutions IF(IHC-P)(1:50-200)
  • Crossreactivity Human, Mouse, Rat
  • Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. Many of the tight junction-associated proteins are members of the membrane-associated guanylate kinase (MAGUK) family and include occludin, ZO-1, ZO-2 and ZO-3 (1,2). These proteins are thought to have both structural and signaling roles, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain (3). ZO-1 forms complexes with either ZO-2 or ZO-3 (4). In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction (5-7). ZO-1 expression is significantly reduced in many breast cancer lines (8). ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue (2,3).
  • Purification Purified by Protein A.
  • Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission 650nm/665nm
  • Synonyms Tight junction protein 3; Tight junction protein ZO-3; Tight junction protein ZO3; TJP3; ZO3;ZO-3; ZO3_HUMAN; Zona occludens protein 3; Zonula occludens protein 3.
  • Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Zonula occludens protein 3 Antibody, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation Alexa Fluor,ALEXA FLUOR 647
  • French translation anticorps