Long name Cyclin E Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known as Anti-Cyclin E PAb ALEXA FLUOR 594
Category Conjugated Primary Antibodies
Conjugated with ALEXA FLUOR® 594
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen Cyclin E
Specificity This is a highly specific antibody against Cyclin E.
Modification Site None
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cyclin E
Gene ID Number 898
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Properties For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.