Beta Glucan Receptor Antibody

  • Catalog name: bs-2455R
  • Supplier name: Bioss Primary Unconjugated Antibodies
  • Size: 0.1ml
  • Price: 263.00€
  • Long name Beta Glucan Receptor Primary Polyclonal Antibody
  • Also known as Beta Glucan Receptor PAb
  • Category Primary Antibodies
  • Conjugation Unconjugated
  • Target Antigen DECTIN-1/beta Glucan Receptor
  • Specificity This is a highly specific antibody against DECTIN-1/beta Glucan Receptor.
  • Modification(s) None
  • Modification site(s) Unmodified antibody
  • Clonality Polyclonal antibody
  • Clone number Polyclonal antibody
  • Concentration 1ug per 1ul
  • Immunogen range 66-110/247
  • Subcellular location Extracellular
  • Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Beta-glucan receptor
  • Gene ID number 64581
  • Swiss Prot Q9BXN2
  • Tested Applications WB, IHC-P, IF(IHC-P)
  • Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity Human, Mouse
  • Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
  • Purification method This antibody was purified via Protein A.
  • Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names BGR; CD369; CANDF4; DECTIN1; CLECSF12; C-type lectin domain family 7 member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1; CLEC7A; UNQ539/PRO1082
  • Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation anticorps