Tau protein(Ser673) Antibody

  • Catalog name: bs-10114R
  • Supplier name: Bioss Primary Unconjugated Antibodies
  • Size: 0.1ml
  • Price: 281.00€
  • Long name Tau protein(Ser673) Primary Polyclonal Antibody
  • Also known as Tau protein(Ser673) PAb
  • Category Primary Antibodies
  • Conjugation Unconjugated
  • Target Antigen Tau protein Ser673
  • Specificity This is a highly specific antibody against Tau protein Ser673.
  • Modification(s) Phosphorylation
  • Modification site(s) Ser673
  • Clonality Polyclonal antibody
  • Clone number Polyclonal antibody
  • Concentration 1ug per 1ul
  • Source KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser673
  • Gene ID number 4137
  • Tested Applications WB, IHC-P, IF(IHC-P)
  • Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity Human, Mouse, Rat
  • Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system
  • Purification method This antibody was purified via Protein A.
  • Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names MAPTphospho S673; p-Tau proteinSer673; MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN.
  • Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation anticorps