GATA3 (Ser308) Antibody

  • Catalog name: bs-13294R
  • Supplier name: Bioss Primary Unconjugated Antibodies
  • Size: 0.1ml
  • Price: 281.00€
  • Long name GATA3 (Ser308) Primary Polyclonal Antibody
  • Also known as GATA3 (Ser308) PAb
  • Category Primary Antibodies
  • Conjugation Unconjugated
  • Target Antigen GATA3 Ser308
  • Specificity This is a highly specific antibody against GATA3 Ser308.
  • Modification(s) Phosphorylation
  • Modification site(s) Ser308
  • Clonality Polyclonal antibody
  • Clone number Polyclonal antibody
  • Concentration 1ug per 1ul
  • Source KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser308
  • Gene ID number 2625
  • Tested Applications WB, IHC-P, IF(IHC-P)
  • Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity Human, Mouse
  • Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
  • Purification method This antibody was purified via Protein A.
  • Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names GATA3 phospho S308; p-GATA3 phospho S308; GATA3 phospho Ser308; p-GATA3 Ser308; GATA 3; GATA3; GATA-3; GATA binding factor 3; GATA binding protein 3; HDR; MGC2346; MGC5199; MGC5445; Trans acting T cell specic transcription factor GATA 3; GATA3_HUMAN; Trans-acting T-cell-specic transcription factor GATA-3; GATA-binding factor 3.
  • Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation anticorps