Rabbit anti Serine/Threonine-protein kinase PINK1 (C-Terminal)

  • Catalog name: X2760P
  • Supplier name: nordc
  • Size: 100 μg
  • Price: 420.00€
  • Category Primary Antibodies
  • Long description Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.
  • Antibody come from n/a
  • Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
  • Clone Polyclonal
  • Antigen-antibody binding interaction Rabbit anti Serine/Threonine-protein kinase PINK1 (C-Terminal) Antibody
  • Antibody is raised in Rabbit
  • Antibody's reacts with Human
  • Antibody's reacts with these species This antibody doesn't cross react with other species
  • Antibody's specificity No Data Available
  • Application Western blot, Immunohistochemistry, EIA
  • Antibody's suited for Optimal concentration should be evaluated by serial dilutions.
  • Storage -20ºC
  • Relevant references no information yet
  • Protein number see ncbi
  • Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • About Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name Oryctolagus cuniculus