Long description p44 MAP Kinase (ERK) belongs to the protein kinase superfamily, the MAP kinase subfamily and contains 1 protein kinase domain It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
Antibody come from GKPIPNPLLGLDST (V5) synthetic peptide conjugated to KLH
Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
Antibody's reacts with these species This antibody doesn't cross react with other species
Antibody's specificity No Data Available
Application WB, IP
Antibody's suited for Sensitivity: WB (with ECL): 1-2 ng of V5-tagged fusion proteins._x000B_WB (with ECL): 1:1000-3000 dilution (incubate for 1 hour at room temperature).IS: 1:500-2000 dilution. For best results with other assays (e.g. Dot, ELISA, IP, etc), optimal concentration should be evaluated by serial dilutions.
Relevant references no information yet
Protein number see ncbi
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.