Mouse anti Influenza A antibody Avian antibody H5N1 antibody Hemagglutinin (HA) (IN) (Bird Flu)
Catalog name: X2590M
Supplier name: nordc
Size: 100 μg
Category Primary Antibodies
Long description Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins_x000B_hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low (4). HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability (5). While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.
Antibody come from Avian flu nucleoprotein amino acids 58-77.
Other description Supplied as a liquid in PBS, 0.05% sodium azide, 0.2% gelatin. Purified by immunoaffinity chromatography.
Antigen-antibody binding interaction Mouse anti Influenza A antibody Avian antibody H5N1 antibody Hemagglutinin (HA) (IN) (Bird Flu) Antibody
Antibody is raised in Mouse
Antibody's reacts with Human
Antibody's reacts with these species This antibody doesn't cross react with other species
Antibody's specificity No Data Available
Application ELISA, WB
Antibody's suited for Western Blot: 0.5-2µg/ml_x000B_Optimal concentration should be evaluated by serial dilutions.
Relevant references no information yet
Protein number see ncbi
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Properties If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Mouse anti Influenza A antibody Avian antibody H5N1 antibody Hemagglutinin (HA) (IN) ( Flu) works on aves samples.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.