Zinc Finger Protein GLI1 - Blocking Peptide

  • Catalog name: X2367B
  • Supplier name: nordc
  • Size: 50 μg
  • Price: 168.00€
  • Category Proteins & Peptides
  • Long description Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.
  • Antibody come from Synthetic peptide derived from human APM2 protein
  • Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide.
  • Clone not specified
  • Antigen-antibody binding interaction Zinc Finger Protein GLI1 - Blocking Peptide
  • Antibody is raised in Rabbit
  • Antibody's reacts with Human
  • Antibody's reacts with these species This antibody doesn't cross react with other species
  • Antibody's specificity No Data Available
  • Application Western blot
  • Antibody's suited for Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Storage -80ºC
  • Relevant references 1. Scott, B.J., et al. APM2 is a novel mediator of cisplatin resistance in a variety of cancer cell types regardless of p53 or MMR status. Int. J. Cancer 2009, 125, 1193-1204
  • Protein number see ncbi
  • Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Test You can block the antibody by the specific target amino acid sequence of peptide.
  • Properties blocking peptide