Long description Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.
Antibody come from Synthetic peptide derived from MCT3 protein.
Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide.
Antibody's reacts with these species This antibody doesn't cross react with other species
Antibody's specificity No Data Available
Application Western blot
Antibody's suited for Antibody can be used for Western blotting (1-5 µg/ml starting dilution). Optimal concentration should be evaluated by serial dilutions.
Relevant references 1. Yoon, H., et al. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.; Genomics 60:366-370(1999)._x000B__x000B_2. Zhu, S., et al. 'Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.' Circulation. 2005 Aug 30;112(9):1353-61._x000B__x000B_3. Philip, N.J., et al. 'Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.' Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11.
Protein number see ncbi
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Test You can block the antibody by the specific target amino acid sequence of peptide.