Chemical available in other sizes
Please inquire size and price
Stock availability
Pending QC
Cas number
This product doesn't have CAS Number
Chemical's molecular weight
643.71
Chemical's main applications
(S)-Isopropyl 2-(((R)-(((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Chemical's formula
C28H43FN3O9PSi
Physical properties
White Solid
Melting temperature
No Data Available
Boiling temperature
No Data Available
Chemical's soluble in
Chloroform, Dichloromethane, Methanol