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Stock availability
Pending QC
Cas number
1256490-31-9
Chemical's molecular weight
408.34
Chemical's main applications
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Chemical's formula
C18H21N2O7P
Physical properties
No Data Available
Melting temperature
No Data Available
Boiling temperature
No Data Available
Chemical's soluble in
Dichloromethane, Ethyl Acetate, Methanol