Indirubin-3’-monoxime

  • Catalog name: I527500
  • Supplier name: trca
  • Size: 1 mg
  • Price: 115.00€
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  • Chemical available in other sizes Please inquire size and price
  • Stock availability In Stock
  • Cas number 160807-49-8
  • Chemical's molecular weight 277.28
  • Chemical's main applications A potent inhibitor of GSK-3ß (IC50=22nM). Also inhibits CDK1 (IC50=180nM) and CDK (IC50=100nM). It reversibly arrests asynchronous HBL-100 cells at G2. It induces apoptosis in the mammary carcinoma cell line MCF-7 (10üM).
  • Chemical's category Inhibitors
  • Other name Indirubin-3’-oxime; 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one;
  • Chemical's formula C16H11N3O2
  • Physical properties Dark Red Solid
  • Melting temperature 247-249°C (dec.)
  • Boiling temperature No Data Available
  • Chemical's soluble in DMSO, Methanol
  • Stability conditions Light Sensitive
  • Storage -20°C Freezer