Recombinant Human Neutrophil Cytosol Factor 1/ NCF1 Protein

  • Catalog name: PKSH032805-10µg
  • Supplier name: Elabscience
  • Size: 10µg
  • Price: 222.00€
  • Check this product
  • Synonym NCF-1;47 kDa autosomal chronic granulomatous disease protein/47 kDa neutrophil oxidase factor;NCF-47K;Neutrophil NADPH oxidase factor 1;Nox organizer 2;Nox-organizing protein 2/SH3 and PX domain-containing protein 1A;p47-phox
  • Activity NA
  • Sequence Met1-Val390
  • Fusion tag C-6His
  • Accession P14598
  • Expressed Host E.coli
  • Shipping The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity >95% as determined by reducing SDS-PAGE.
  • Endotoxin <1.0 EU per µg as determined by LAL test.
  • Stability and Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass 45.6 kDa
  • AP Mol Mass 45-50 kDa
  • Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris 100mM NaCl,1mM DTT, pH8.0.
  • Background Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and plays an important role in innate immunity, producing reactive oxygen species and reducing the severity and duration of parasitic infection and autoimmune disease. NCF1 also has a role in T cell activation.
  • Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source Recombinants or rec. proteins
  • Group recombinants