N-[(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester (Mixture)

  • Catalog name: N497035
  • Supplier name: trca
  • Size: 10 mg
  • Price: 340.00€
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  • Chemical available in other sizes Please inquire size and price
  • Stock availability Pending QC
  • Cas number This product doesn't have CAS Number
  • Chemical's molecular weight 408.34
  • Chemical's main applications N-[(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester Mixture is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
  • Other name Isopropyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate
  • Chemical's formula C18H21N2O7P
  • Physical properties No Data Available
  • Melting temperature No Data Available
  • Boiling temperature No Data Available
  • Chemical's soluble in Dichloromethane, Ethyl Acetate, Methanol
  • Stability conditions No Data Available
  • Storage No Data Available