Catalog name: A621350

Supplier name: trca

Size: 500 µg

Price: 123.00€

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Stock availability In Stock

Cas number 545380-34-5

Chemical's molecular weight 356.42

Chemical's main applications QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways.

Chemical's category Amines, Aromatics, Heterocycles, Inhibitors

Other name N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine; QNZ;

Chemical's formula C22H20N4O

Physical properties Off-White to Brownish-Yellow Solid

Melting temperature >170°C (dec.)

Boiling temperature No Data Available

Chemical's soluble in DMSO, Methanol (Sparingly)

Stability conditions No Data Available

Storage Refrigerator, Under Inert Atmosphere

6-Amino-4-(4-phenoxyphenylethylamino)quinazoline